DMEM Low Glucose Cytiva®

Advancing Cell Culture with DMEM Low Glucose

DMEM/Low: with 1000 mg/L glucose, 4.0 mM L-glutamine, and 110 mg/L sodium pyruvate

DMEM Low Glucose represents a pivotal modification derived from Basal Medium Eagle (BME) originally designed for the cultivation of mouse embryonic cells. This versatile medium has since found widespread utility across various immortalized cell lines sourced from diverse species including humans, monkeys, hamsters, rats, mice, chicken, and fish. One of its hallmark features is its enhanced composition, boasting fourfold higher concentrations of essential amino acids, vitamins, and supplementary components compared to its precursor, Basal Medium Eagle (BME).

An essential characteristic of DMEM lies in its formulation devoid of growth-promoting agents or proteins, underscoring the importance of supplementing it with Fetal Bovine Serum (FBS) for achieving optimal cellular performance. Moreover, its specific glucose concentration of 5.6 mM renders it conducive for supporting cellular proliferation and metabolic activities.

Optimal Cellular Functionality with FBS Supplementation

Furthermore, DMEM Low Glucose is manufactured utilizing Water for Injection (WFI) quality water to ensure stringent quality standards. Its production process includes a meticulous 0.1 μm sterile filtration step, safeguarding against potential microbial contamination. Emphasizing quality assurance, its manufacturing adheres to ISO 9001:2000 certified processes, signifying a commitment to excellence and consistency in product quality.

In summary, DMEM Low Glucose stands as a cornerstone medium in cell culture, offering researchers a reliable and enriched substrate for the propagation and study of a wide array of cell types across various experimental contexts.

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